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Light Chain Stabilization: A Therapeutic Approach to Ameliorate AL Amyloidosis

Non-native immunoglobulin light chain conformations, including aggregates, appear to cause light chain amyloidosis pathology. Despite significant progress in pharmacological eradication of the neoplastic plasma cells that secrete these light chains, in many patients impaired organ function remains....

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Detalles Bibliográficos
Autores principales: Morgan, Gareth J., Buxbaum, Joel N., Kelly, Jeffery W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218996/
https://www.ncbi.nlm.nih.gov/pubmed/35757512
http://dx.doi.org/10.3390/hemato2040042