Celastrol Inhibited Human Esophageal Cancer by Activating DR5-Dependent Extrinsic and Noxa/Bim-Dependent Intrinsic Apoptosis

Esophageal squamous cell carcinoma (ESCC) is one of the deadliest digestive system cancers worldwide lacking effective therapeutic strategies. Recently, it has been found that the natural product celastrol plays an anti-cancer role in several human cancers by inducing cell cycle arrest and apoptosis...

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Detalles Bibliográficos
Autores principales: Chen, Xihui, Wang, Shiwen, Zhang, Li, Yuan, Shuying, Xu, Tong, Zhu, Feng, Zhang, Yanmei, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219015/
https://www.ncbi.nlm.nih.gov/pubmed/35754502
http://dx.doi.org/10.3389/fphar.2022.873166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219015/
https://www.ncbi.nlm.nih.gov/pubmed/35754502
http://dx.doi.org/10.3389/fphar.2022.873166

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