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Celastrol Inhibited Human Esophageal Cancer by Activating DR5-Dependent Extrinsic and Noxa/Bim-Dependent Intrinsic Apoptosis
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest digestive system cancers worldwide lacking effective therapeutic strategies. Recently, it has been found that the natural product celastrol plays an anti-cancer role in several human cancers by inducing cell cycle arrest and apoptosis...
Autores principales: | Chen, Xihui, Wang, Shiwen, Zhang, Li, Yuan, Shuying, Xu, Tong, Zhu, Feng, Zhang, Yanmei, Jia, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219015/ https://www.ncbi.nlm.nih.gov/pubmed/35754502 http://dx.doi.org/10.3389/fphar.2022.873166 |
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