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Single-Site Mutation Induces Water-Mediated Promiscuity in Lignin Breaking Cytochrome P450(GcoA)

[Image: see text] Cytochrome P450(GcoA) is an enzyme that catalyzes the guaiacol unit of lignin during the lignin breakdown via an aryl-O-demethylation reaction. This reaction is intriguing and is of commercial importance for its potential applications in the production of biofuel and plastic from b...

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Detalles Bibliográficos
Autores principales: Singh, Warispreet, Santos, Sónia F. G., James, Paul, Black, Gary W., Huang, Meilan, Dubey, Kshatresh Dutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219061/
https://www.ncbi.nlm.nih.gov/pubmed/35755387
http://dx.doi.org/10.1021/acsomega.2c00524