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C(sp(3))-Arylation by Conformationally Accelerated Intramolecular Nucleophilic Aromatic Substitution (S(N)Ar)
[Image: see text] The asymmetric synthesis of heavily substituted benzylic stereogenic centers, prevalent in natural products, therapeutics, agrochemicals, and catalysts, is an ongoing challenge. In this Account, we outline our contribution to this endeavor, describing our discovery of a series of n...
Autores principales: | Wales, Steven M., Saunthwal, Rakesh K., Clayden, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219115/ https://www.ncbi.nlm.nih.gov/pubmed/35620846 http://dx.doi.org/10.1021/acs.accounts.2c00184 |
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