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Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

Currently, there is a need for diagnostic markers in Lewy body disorders (LBD). α-synuclein (αSyn) RT-QuIC has emerged as a promising assay to detect misfolded αSyn in clinically or neuropathologically established patients with various synucleinopathies. In this study, αSyn RT-QuIC was used to analy...

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Detalles Bibliográficos
Autores principales: Hall, Sara, Orrù, Christina D., Serrano, Geidy E., Galasko, Douglas, Hughson, Andrew G., Groveman, Bradley R., Adler, Charles H., Beach, Thomas G., Caughey, Byron, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219141/
https://www.ncbi.nlm.nih.gov/pubmed/35733234
http://dx.doi.org/10.1186/s40478-022-01388-7