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Bacterial Lipopolysaccharide as a Negative Predictor of Adjuvant Gemcitabine Efficacy in Pancreatic Cancer

Adjuvant gemcitabine (aGC) is one standard of care after pancreatic ductal adenocarcinoma (PDAC) resection. No biomarker for its efficacy is established. As bacteria mediate gemcitabine resistance, we analyzed whether lipopolysaccharide (LPS) as surrogate for bacterial colonization is prognostic in...

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Detalles Bibliográficos
Autores principales: Guenther, Michael, Gil, Lina, Surendran, Sai Agash, Palm, Melanie Alexandra, Heinemann, Volker, von Bergwelt-Baildon, Michael, Mayerle, Julia, Engel, Jutta, Werner, Jens, Boeck, Stefan, Ormanns, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219162/
https://www.ncbi.nlm.nih.gov/pubmed/35587155
http://dx.doi.org/10.1093/jncics/pkac039