Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway

Aberrant cortisol and activation of the glucocorticoid receptor (GR) play an essential role in age-related progression of Alzheimer's disease (AD). However, the GR pathways required for influencing the pathobiology of AD dementia remain unknown. To address this, we studied an early phase of AD-...

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Detalles Bibliográficos
Autores principales: Dromard, Yann, Arango-Lievano, Margarita, Borie, Amelie, Dedin, Maheva, Fontanaud, Pierre, Torrent, Joan, Garabedian, Michael J., Ginsberg, Stephen D., Jeanneteau, Freddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219215/
https://www.ncbi.nlm.nih.gov/pubmed/35733193
http://dx.doi.org/10.1186/s40478-022-01396-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219215/
https://www.ncbi.nlm.nih.gov/pubmed/35733193
http://dx.doi.org/10.1186/s40478-022-01396-7

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