Cargando…

Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway

Aberrant cortisol and activation of the glucocorticoid receptor (GR) play an essential role in age-related progression of Alzheimer's disease (AD). However, the GR pathways required for influencing the pathobiology of AD dementia remain unknown. To address this, we studied an early phase of AD-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dromard, Yann, Arango-Lievano, Margarita, Borie, Amelie, Dedin, Maheva, Fontanaud, Pierre, Torrent, Joan, Garabedian, Michael J., Ginsberg, Stephen D., Jeanneteau, Freddy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219215/ https://www.ncbi.nlm.nih.gov/pubmed/35733193 http://dx.doi.org/10.1186/s40478-022-01396-7

Ejemplares similares

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors
por: Arango-Lievano, Margarita, et al.
Publicado: (2019)

Dual imaging of dendritic spines and mitochondria in vivo reveals hotspots of plasticity and metabolic adaptation to stress
por: Dromard, Yann, et al.
Publicado: (2021)

Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders
por: Jeanneteau, Freddy, et al.
Publicado: (2016)

Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology
por: Arango-Lievano, Margarita, et al.
Publicado: (2016)

Glucocorticoid receptor action in metabolic and neuronal function
por: Garabedian, Michael J., et al.
Publicado: (2017)

The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex
por: Jeanneteau, Freddy, et al.
Publicado: (2018)

Neurological diseases as primary gliopathies: a reassessment of neurocentrism
por: Verkhratsky, Alexei, et al.
Publicado: (2012)

Effect of neurocentral cartilage destruction on spinal growth in immature rabbits
por: Wen, Jie, et al.
Publicado: (2019)

Fungicide Residues Exposure and [Formula: see text] Aggregation in a Mouse Model of Alzheimer’s Disease
por: Lafon, Pierre-André, et al.
Publicado: (2020)

Psoriasis, Is It a Microdamage of Our “Sixth Sense”? A Neurocentric View
por: Sonkodi, Balázs
Publicado: (2022)

Origins of the Resting-State Functional MRI Signal: Potential Limitations of the “Neurocentric” Model
por: Lu, Hanbing, et al.
Publicado: (2019)

Osteology of Galeamopus pabsti sp. nov. (Sauropoda: Diplodocidae), with implications for neurocentral closure timing, and the cervico-dorsal transition in diplodocids
por: Tschopp, Emanuel, et al.
Publicado: (2017)

Should We Void Lactate in the Pathophysiology of Delayed Onset Muscle Soreness? Not So Fast! Let’s See a Neurocentric View!
por: Sonkodi, Balázs
Publicado: (2022)

Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice
por: Hemonnot-Girard, Anne-Laure, et al.
Publicado: (2022)

High-Pressure Response of Amyloid Folds
por: Torrent, Joan, et al.
Publicado: (2019)

Real-Time Fast Amyloid Seeding and Translocation of α-Synuclein with a Nanopipette
por: Meyer, Nathan, et al.
Publicado: (2022)

Phosphorylation of FE65 Ser(610) by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing
por: Chow, Wan Ning Vanessa, et al.
Publicado: (2015)

Role of Phosphorylation in the Modulation of the Glucocorticoid Receptor’s Intrinsically Disordered Domain
por: Kumar, Raj, et al.
Publicado: (2019)

The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching
por: Jeanneteau, Freddy, et al.
Publicado: (2010)

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression
por: Lynch, James T, et al.
Publicado: (2010)

SUN-LB53 Role of the Glucocorticoid Receptor Phosphorylation in Neural Development
por: Silswal, Neeru, et al.
Publicado: (2020)

Phosphorylation modifies the molecular stability of β-amyloid deposits
por: Rezaei-Ghaleh, Nasrollah, et al.
Publicado: (2016)

Dunce Phosphodiesterase Acts as a Checkpoint for Drosophila Long-Term Memory in a Pair of Serotonergic Neurons
por: Scheunemann, Lisa, et al.
Publicado: (2018)

Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation
por: Kumar, Raj, et al.
Publicado: (2008)

Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta
por: Lopez Sanchez, M. Isabel G., et al.
Publicado: (2017)

Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain
por: Horie, Kanta, et al.
Publicado: (2020)

Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia
por: Ledo, Jose Henrique, et al.
Publicado: (2020)

Site-specific and dose-dependent effects of glucocorticoid receptor phosphorylation in yeast Saccharomyces cerevisiae
por: Popovic, Natasa, et al.
Publicado: (2010)

Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor
por: Khan, Shagufta H., et al.
Publicado: (2017)

Differential Phosphorylation of the Glucocorticoid Receptor in Hippocampal Subregions Induced by Contextual Fear Conditioning Training
por: Ponce-Lina, Renata, et al.
Publicado: (2020)

Viral Infection Increases Glucocorticoid-Induced Interleukin-10 Production through ERK-Mediated Phosphorylation of the Glucocorticoid Receptor in Dendritic Cells: Potential Clinical Implications
por: Ng, Sinnie Sin Man, et al.
Publicado: (2013)

Investigation of α‐Synuclein and Amyloid‐β(42)‐E22Δ Oligomers Using SiN Nanopore Functionalized with L‐Dopa
por: Abrao‐Nemeir, Imad, et al.
Publicado: (2022)

Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation
por: Zatsepina, O. G., et al.
Publicado: (2018)

Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas
por: den Haan, Jurre, et al.
Publicado: (2018)

Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation()
por: Webster Marketon, Jeanette I., et al.
Publicado: (2013)

Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation
por: Ivy, Jessica Ruth, et al.
Publicado: (2019)

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
por: Anacker, C, et al.
Publicado: (2011)

Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds
por: Nakamura, Ryosuke, et al.
Publicado: (2020)

Exploring New Biological Functions of Amyloids: Bacteria Cell Agglutination Mediated by Host Protein Aggregation
por: Torrent, Marc, et al.
Publicado: (2012)

Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells
por: Ather, J L, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_70q99g4fmorqlm6jjq7o82sb61