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Metabolic sensor O-GlcNAcylation regulates erythroid differentiation and globin production via BCL11A
BACKGROUND: Human erythropoiesis is a tightly regulated, multistep process encompassing the differentiation of hematopoietic stem cells (HSCs) toward mature erythrocytes. Cellular metabolism is an important regulator of cell fate determination during the differentiation of HSCs. However, how O-GlcNA...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219246/ https://www.ncbi.nlm.nih.gov/pubmed/35739577 http://dx.doi.org/10.1186/s13287-022-02954-5 |