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Metabolic sensor O-GlcNAcylation regulates erythroid differentiation and globin production via BCL11A

BACKGROUND: Human erythropoiesis is a tightly regulated, multistep process encompassing the differentiation of hematopoietic stem cells (HSCs) toward mature erythrocytes. Cellular metabolism is an important regulator of cell fate determination during the differentiation of HSCs. However, how O-GlcNA...

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Detalles Bibliográficos
Autores principales: Luanpitpong, Sudjit, Kang, Xing, Janan, Montira, Thumanu, Kanjana, Li, Jingting, Kheolamai, Pakpoom, Issaragrisil, Surapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219246/
https://www.ncbi.nlm.nih.gov/pubmed/35739577
http://dx.doi.org/10.1186/s13287-022-02954-5