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Effect of age on human ACE2 and ACE2-expressing alveolar type II cells levels

BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19. Viral entry requires ACE2 and transmembrane protease serine 2 (TMPRSS2). Transcriptomic studies showed that children display lower ACE2 than adul...

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Detalles Bibliográficos
Autores principales: Silva, Mauro G., Falcoff, Nora L., Corradi, Gerardo R., Di Camillo, Norma, Seguel, Rolando F., Tabaj, Gabriela C., Guman, Gabriela R., de Matteo, Elena, Nuñez, Myriam, Gironacci, Mariela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219367/
https://www.ncbi.nlm.nih.gov/pubmed/35739259
http://dx.doi.org/10.1038/s41390-022-02163-z