Cargando…

Effect of age on human ACE2 and ACE2-expressing alveolar type II cells levels

BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19. Viral entry requires ACE2 and transmembrane protease serine 2 (TMPRSS2). Transcriptomic studies showed that children display lower ACE2 than adul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Silva, Mauro G., Falcoff, Nora L., Corradi, Gerardo R., Di Camillo, Norma, Seguel, Rolando F., Tabaj, Gabriela C., Guman, Gabriela R., de Matteo, Elena, Nuñez, Myriam, Gironacci, Mariela M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Clinical Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219367/ https://www.ncbi.nlm.nih.gov/pubmed/35739259 http://dx.doi.org/10.1038/s41390-022-02163-z

Ejemplares similares

Renin-angiotensin system blockade on angiotensin-converting enzyme 2 and TMPRSS2 in human type II pneumocytes
por: Silva, Mauro G., et al.
Publicado: (2022)

ACE2 and Diabetes: ACE of ACEs?
por: Batlle, Daniel, et al.
Publicado: (2010)

ACE2 internalization induced by a SARS-CoV-2 recombinant protein is modulated by angiotensin II type 1 and bradykinin 2 receptors
por: Portales, Andrea Estefanía, et al.
Publicado: (2022)

Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
por: Jacobs, Merel, et al.
Publicado: (2021)

Role of ACE, ACE2 and Neprilysin in the Kidney
por: Chappell, Mark C.
Publicado: (2007)

Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling
por: Clarke, Nicola E., et al.
Publicado: (2012)

Recombinant human ACE2: acing out angiotensin II in ARDS therapy
por: Zhang, Haibo, et al.
Publicado: (2017)

ACE inhibitors on ACE1, ACE2, and TMPRSS2 expression and spheroid attachment on human endometrial Ishikawa cells
por: Fernando, Sudini R., et al.
Publicado: (2022)

Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients
por: Akbari, Mohammadarian, et al.
Publicado: (2022)

Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice
por: Tyrankiewicz, Urszula, et al.
Publicado: (2021)

ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
por: Lee, Ivan T., et al.
Publicado: (2020)

Membrane-associated zinc peptidase families: comparing ACE and ACE2
por: Guy, J.L., et al.
Publicado: (2005)

Sex differences in the lung ACE/ACE2 balance in hypertensive rats
por: Martins, Flavia L., et al.
Publicado: (2021)

ACE and ACE2: insights from Drosophila and implications for COVID-19
por: Herrera, Paul, et al.
Publicado: (2021)

ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men
por: Martínez-Gómez, Laura E., et al.
Publicado: (2022)

Is hypertension in African-descent populations contributed to by an imbalance in the activities of the ACE2/Ang-(1-7)/Mas and the ACE/Ang II/AT(1) axes?
por: Cohall, Damian, et al.
Publicado: (2020)

ACE2 Receptor and Its Isoform Short-ACE2 Are Expressed on Human Spermatozoa
por: Ramal-Sanchez, Marina, et al.
Publicado: (2022)

Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse
por: Roca-Ho, Heleia, et al.
Publicado: (2017)

Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease
por: Sabater Molina, Maria, et al.
Publicado: (2022)

ACE2 is not induced by interferon
por: Saffern, Miriam
Publicado: (2020)

The specific applications of the TSR-based method in identifying Zn(2+) binding sites of proteases and ACE/ACE2
por: Sarkar, Titli, et al.
Publicado: (2022)

ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study
por: Gill, Dipender, et al.
Publicado: (2020)

Entropic contribution of ACE2 glycans to RBD binding
por: Mugnai, Mauro L., et al.
Publicado: (2023)

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein
por: Calcagnile, Matteo, et al.
Publicado: (2021)

Reduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibition
por: Velkoska, Elena, et al.
Publicado: (2009)

Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome
por: Gómez, Juan, et al.
Publicado: (2020)

ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging
por: Joshi, S., et al.
Publicado: (2020)

Genotype variation of ACE and ACE2 genes affects the severity of COVID-19 patients
por: Faustine, Ingrid, et al.
Publicado: (2023)

Comparative docking studies to understand the binding affinity of nicotine with soluble ACE2 (sACE2)-SARS-CoV-2 complex over sACE2
por: C., Selvaa Kumar, et al.
Publicado: (2020)

The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19
por: Bosso, Mira, et al.
Publicado: (2020)

In silico study of intrinsic dynamics of full-length apo-ACE2 and RBD-ACE2 complex
por: Liu, Qing, et al.
Publicado: (2021)

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects
por: Jacobs, Merel, et al.
Publicado: (2020)

Variability in digestive and respiratory tract Ace2 expression is associated with the microbiome
por: Koester, Sean T., et al.
Publicado: (2021)

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
por: Mou, Huihui, et al.
Publicado: (2020)

Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients
por: Osman, Ikram Omar, et al.
Publicado: (2021)

ACE2 – das missbrauchte Multitalent
por: Bader, M.
Publicado: (2020)

ACE2: The Only Thing That Matters?
por: Sanchez-David, Raul Y., et al.
Publicado: (2020)

ACE2, Metformin, and COVID-19
por: Malhotra, Atul, et al.
Publicado: (2020)

Pharmacologic modulation of ACE2 expression
por: Soler, María José, et al.
Publicado: (2008)

ACE/ACE2 Ratio and MMP-9 Activity as Potential Biomarkers in Tuberculous Pleural Effusions
por: Hsieh, Wen-Yeh, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2ti2mjoeq3kjrlapb28ploiqli