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Modeling the Effects of Maternal Diabetes on the Developing Human Heart Using Pluripotent Stem Cell–Derived Heart Organoids

Congenital heart defects (CHD) constitute the most common type of birth defect in humans. Maternal diabetes during the first trimester of pregnancy (pregestational diabetes, or PGD) is one of the most prominent factors contributing to CHD, and is present in a significant population of female patient...

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Detalles Bibliográficos
Autores principales: Lewis‐Israeli, Yonatan R., Abdelhamid, Mishref, Olomu, Isoken, Aguirre, Aitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219413/
https://www.ncbi.nlm.nih.gov/pubmed/35723517
http://dx.doi.org/10.1002/cpz1.461