Cargando…

Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs

Genome-wide association studies (GWASs) have identified hundreds of loci associated with psychiatric diseases, yet there is a lack of understanding of disease pathophysiology. Common risk variants can shed light on the underlying molecular mechanisms; however, identifying causal variants remains cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez-Priego, Carlos, Hu, Ruiqi, Boshans, Linda L., Lalli, Matthew, Janas, Justyna A., Williams, Sarah E., Dong, Zhiqiang, Yang, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219592/
https://www.ncbi.nlm.nih.gov/pubmed/35649373
http://dx.doi.org/10.1016/j.celrep.2022.110877