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Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs
Genome-wide association studies (GWASs) have identified hundreds of loci associated with psychiatric diseases, yet there is a lack of understanding of disease pathophysiology. Common risk variants can shed light on the underlying molecular mechanisms; however, identifying causal variants remains cha...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219592/ https://www.ncbi.nlm.nih.gov/pubmed/35649373 http://dx.doi.org/10.1016/j.celrep.2022.110877 |