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TGFβ1 Induces Senescence and Attenuated VEGF Production in Retinal Pericytes

Diabetic retinopathy (DR) is a microvascular disease of the retina and a serious complication of type I and type II diabetes mellitus. DR affects working-age populations and can cause permanent vision loss if left untreated. The standard of care for proliferative DR is inhibiting VEGF. However, the...

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Detalles Bibliográficos
Autores principales: Avramovic, Dragana, Archaimbault, Sébastien A., Kemble, Alicia M., Gruener, Sabine, Lazendic, Mirjana, Westenskow, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219633/
https://www.ncbi.nlm.nih.gov/pubmed/35740425
http://dx.doi.org/10.3390/biomedicines10061404