PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1

Emerging evidence shows that peroxisome proliferator-activated receptor delta (PPARδ) plays a pivotal role in cellular aging. However, its function in retinal disease processes such as hyperglycemia-associated diabetic retinopathy is unclear. Here, we demonstrate that PPARδ inhibits premature senesc...

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Detalles Bibliográficos
Autores principales: Lee, Eun Ji, Won, Jun Pil, Lee, Hyuk Gyoon, Kim, Eunsu, Hur, Jinwoo, Lee, Won Jin, Hwang, Jung Seok, Seo, Han Geuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219651/
https://www.ncbi.nlm.nih.gov/pubmed/35740104
http://dx.doi.org/10.3390/antiox11061207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219651/
https://www.ncbi.nlm.nih.gov/pubmed/35740104
http://dx.doi.org/10.3390/antiox11061207

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