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Theophylline Induces Remyelination and Functional Recovery in a Mouse Model of Peripheral Neuropathy

Charcot-Marie-Tooth disease (CMT) is a large group of inherited peripheral neuropathies that are primarily due to demyelination and/or axonal degeneration. CMT type 1A (CMT1A), which is caused by the duplication of the peripheral myelin protein 22 (PMP22) gene, is a demyelinating and the most freque...

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Detalles Bibliográficos
Autores principales: Duman, Mert, Jaggi, Stephanie, Enz, Lukas Simon, Jacob, Claire, Schaeren-Wiemers, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219657/
https://www.ncbi.nlm.nih.gov/pubmed/35740439
http://dx.doi.org/10.3390/biomedicines10061418