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Direct Derivatization in Dried Blood Spots for Oxidized and Reduced Glutathione Quantification in Newborns
The glutathione (GSH)-to-glutathione disulfide (GSSG) ratio is an essential node contributing to intracellular redox status. GSH/GSSG determination in whole blood can be accomplished by liquid chromatography–mass spectrometry (LC-MS) after the derivatization of GSH with N-ethylmaleimide (NEM). While...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219658/ https://www.ncbi.nlm.nih.gov/pubmed/35740062 http://dx.doi.org/10.3390/antiox11061165 |