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Direct Derivatization in Dried Blood Spots for Oxidized and Reduced Glutathione Quantification in Newborns

The glutathione (GSH)-to-glutathione disulfide (GSSG) ratio is an essential node contributing to intracellular redox status. GSH/GSSG determination in whole blood can be accomplished by liquid chromatography–mass spectrometry (LC-MS) after the derivatization of GSH with N-ethylmaleimide (NEM). While...

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Detalles Bibliográficos
Autores principales:	Ten-Doménech, Isabel, Solaz-García, Álvaro, Lara-Cantón, Inmaculada, Pinilla-Gonzalez, Alejandro, Parra-Llorca, Anna, Vento, Máximo, Quintás, Guillermo, Kuligowski, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219658/ https://www.ncbi.nlm.nih.gov/pubmed/35740062 http://dx.doi.org/10.3390/antiox11061165

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