Enhanced Anxiety and Olfactory Microglial Activation in Early-Stage Familial Alzheimer’s Disease Mouse Model

SIMPLE SUMMARY: We observed that compared to wildtype (WT) littermates, 5 × FAD mice showed enhanced anxiety with concomitant increased pro-inflammatory cytokines in the olfactory bulb (OB) but not the frontal cortex (FC) at as early as 2 months old (mo). More prominent microglial activation and mor...

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Detalles Bibliográficos
Autores principales: Chithanathan, Keerthana, Xuan, Fang-Ling, Hickey, Miriam Ann, Tian, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219751/
https://www.ncbi.nlm.nih.gov/pubmed/35741458
http://dx.doi.org/10.3390/biology11060938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219751/
https://www.ncbi.nlm.nih.gov/pubmed/35741458
http://dx.doi.org/10.3390/biology11060938

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