Cargando…

A Narrative Review of (99m)Tc-Aprotinin in the Diagnosis of Cardiac Amyloidosis and a New Life for an Unfairly Abandoned Drug

Several studies investigated the use of (99m)Tc-labelled Aprotinin as an amyloid seeker some years ago. In vitro tests showed high binding affinity for several types of amyloid fibrils accompanied by an excellent specificity. Initial human studies demonstrated good accuracy in detecting cardiac invo...

Descripción completa

Detalles Bibliográficos
Autores principales: Aprile, Carlo, Lodola, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219762/
https://www.ncbi.nlm.nih.gov/pubmed/35740399
http://dx.doi.org/10.3390/biomedicines10061377