The Intricate Epigenetic and Transcriptional Alterations in Pediatric High-Grade Gliomas: Targeting the Crosstalk as the Oncogenic Achilles’ Heel

Pediatric high-grade gliomas (pHGGs) are a deadly and heterogenous subgroup of gliomas for which the development of innovative treatments is urgent. Advances in high-throughput molecular techniques have shed light on key epigenetic components of these diseases, such as K27M and G34R/V mutations on h...

Descripción completa

Detalles Bibliográficos
Autores principales: Huchedé, Paul, Leblond, Pierre, Castets, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219798/
https://www.ncbi.nlm.nih.gov/pubmed/35740334
http://dx.doi.org/10.3390/biomedicines10061311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219798/
https://www.ncbi.nlm.nih.gov/pubmed/35740334
http://dx.doi.org/10.3390/biomedicines10061311

Ejemplares similares