A Simple Method for the Prediction of Human Concentration–Time Profiles and Pharmacokinetics of Antibody–Drug Conjugates (ADC) from Rats or Monkeys

Knowledge of human concentration–time profiles from animal data can be useful during early drug development. The objective of this study is to predict human concentration–time profiles of antibody–drug conjugates (ADCs) and subsequently predict pharmacokinetic parameters in humans from rats or monke...

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Detalles Bibliográficos
Autor principal: Mahmood, Iftekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219807/
https://www.ncbi.nlm.nih.gov/pubmed/35735361
http://dx.doi.org/10.3390/antib11020042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219807/
https://www.ncbi.nlm.nih.gov/pubmed/35735361
http://dx.doi.org/10.3390/antib11020042

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