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Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a genetic neurodegenerative disease characterized by motor, psychiatric, and cognitive symptoms. Emerging evidence suggests that emotional and cognitive deficits seen in HD may be related to hippocampal dysfunction. We used the YAC128 HD mouse model to perform a temporal...

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Detalles Bibliográficos
Autores principales: de Paula Nascimento-Castro, Cristine, Winkelmann-Duarte, Elisa C., Mancini, Gianni, Welter, Priscilla Gomes, Plácido, Evelini, Farina, Marcelo, Gil-Mohapel, Joana, Rodrigues, Ana Lúcia S., de Bem, Andreza Fabro, Brocardo, Patricia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219853/
https://www.ncbi.nlm.nih.gov/pubmed/35740454
http://dx.doi.org/10.3390/biomedicines10061433