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Reversion of MRAP2 Protein Sequence Generates a Functional Novel Pharmacological Modulator for MC4R Signaling

SIMPLE SUMMARY: Reversion of the wild-type protein sequences of single transmembrane melanocortin accessory protein families (MRAP2) in mice and zebrafish created novel functional pharmacological modulators for regulating melanocortin 4 receptor (MC4R) signaling. All of the brand new reversed MRAP2...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Wang, Meng, Fu, Yanbin, Zhang, Cong, Kuang, Zhe, Bian, Shan, Wan, Rui, Qu, Shen, Zhang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219869/
https://www.ncbi.nlm.nih.gov/pubmed/35741395
http://dx.doi.org/10.3390/biology11060874