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DNA Methylation and Gene Expression in Blood and Adipose Tissue of Adult Offspring of Women with Diabetes in Pregnancy—A Validation Study of DNA Methylation Changes Identified in Adolescent Offspring

Maternal gestational diabetes and obesity are associated with adverse outcomes in offspring, including increased risk of diabetes and cardiovascular diseases. Previously, we identified a lower DNA methylation degree at genomic sites near the genes ESM1, MS4A3, and TSPAN14 in the blood cells of adole...

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Detalles Bibliográficos
Autores principales: Manitta, Eleonora, Fontes Marques, Irene Carolina, Stokholm Bredgaard, Sandra, Kelstrup, Louise, Houshmand-Oeregaard, Azadeh, Dalsgaard Clausen, Tine, Groth Grunnet, Louise, Reinhardt Mathiesen, Elisabeth, Torp Dalgaard, Louise, Barrès, Romain, Vaag, Allan Arthur, Damm, Peter, Hjort, Line
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219870/
https://www.ncbi.nlm.nih.gov/pubmed/35740266
http://dx.doi.org/10.3390/biomedicines10061244