Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells

Thymidylate synthase (TYMS) is the crucial enzymatic precursor for DNA biosynthesis and, therefore, the critical target for numerous types of chemotherapy, including the most frequently applied agent in colon cancer treatment 5-fluorouracil (5-FU). TYMS also seems to be associated with cancer metast...

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Detalles Bibliográficos
Autores principales: Ciszewski, Wojciech M., Chmielewska-Kassassir, Małgorzata, Wozniak, Lucyna A., Sobierajska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219882/
https://www.ncbi.nlm.nih.gov/pubmed/35740289
http://dx.doi.org/10.3390/biomedicines10061267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219882/
https://www.ncbi.nlm.nih.gov/pubmed/35740289
http://dx.doi.org/10.3390/biomedicines10061267

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