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Natriuretic Peptide-Based Novel Therapeutics: Long Journeys of Drug Developments Optimized for Disease States

SIMPLE SUMMARY: Natriuretic peptides are endogenous hormones produced in the heart and vascular endothelium, and they enable cardiorenal protective actions or bone growth via cGMP stimulation through their receptor guanylyl cyclase receptor A or B. To optimize the drug for each disease state, we mus...

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Detalles Bibliográficos
Autores principales: Ichiki, Tomoko, Jinno, Atsushi, Tsuji, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219923/
https://www.ncbi.nlm.nih.gov/pubmed/35741380
http://dx.doi.org/10.3390/biology11060859