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Altered Mitochondrial Opa1-Related Fusion in Mouse Promotes Endothelial Cell Dysfunction and Atherosclerosis

Flow (shear stress)-mediated dilation (FMD) of resistance arteries is a rapid endothelial response involved in tissue perfusion. FMD is reduced early in cardiovascular diseases, generating a major risk factor for atherosclerosis. As alteration of mitochondrial fusion reduces endothelial cells’ (ECs)...

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Detalles Bibliográficos
Autores principales: Chehaitly, Ahmad, Guihot, Anne-Laure, Proux, Coralyne, Grimaud, Linda, Aurrière, Jade, Legouriellec, Benoit, Rivron, Jordan, Vessieres, Emilie, Tétaud, Clément, Zorzano, Antonio, Procaccio, Vincent, Joubaud, Françoise, Reynier, Pascal, Lenaers, Guy, Loufrani, Laurent, Henrion, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219969/
https://www.ncbi.nlm.nih.gov/pubmed/35739974
http://dx.doi.org/10.3390/antiox11061078