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Extracellular Signal-Regulated Kinase 1 Alone Is Dispensable for Hyperoxia-Mediated Alveolar and Pulmonary Vascular Simplification in Neonatal Mice

Bronchopulmonary dysplasia (BPD) is a morbid lung disease distinguished by lung alveolar and vascular simplification. Hyperoxia, an important BPD causative factor, increases extracellular signal-regulated kinases (ERK)-1/2 expression, whereas decreased lung endothelial cell ERK2 expression reduces a...

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Detalles Bibliográficos
Autores principales: Menon, Renuka T., Thapa, Shyam, Shrestha, Amrit Kumar, Barrios, Roberto, Shivanna, Binoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219973/
https://www.ncbi.nlm.nih.gov/pubmed/35740027
http://dx.doi.org/10.3390/antiox11061130