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Hormonal and Genetic Regulatory Events in Breast Cancer and Its Therapeutics: Importance of the Steroidogenic Acute Regulatory Protein

Estrogen promotes the development and survival of the majority of breast cancers (BCs). Aromatase is the rate-limiting enzyme in estrogen biosynthesis, and it is immensely expressed in both cancerous and non-cancerous breast tissues. Endocrine therapy based on estrogen blockade, by aromatase inhibit...

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Detalles Bibliográficos
Autores principales: Manna, Pulak R., Ahmed, Ahsen U., Molehin, Deborah, Narasimhan, Madhusudhanan, Pruitt, Kevin, Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220045/
https://www.ncbi.nlm.nih.gov/pubmed/35740335
http://dx.doi.org/10.3390/biomedicines10061313