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Yin and Yang of NADPH Oxidases in Myocardial Ischemia-Reperfusion

Oxidative stress is critically involved in the pathophysiology of myocardial ischemic-reperfusion (I/R) injury. NADPH oxidase (Nox) 2 and 4, major sources of reactive oxygen species (ROS) in cardiomyocytes, are upregulated in response to I/R. Suppression of Nox-derived ROS prevents mitochondrial dys...

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Detalles Bibliográficos
Autores principales: Matsushima, Shouji, Sadoshima, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220061/
https://www.ncbi.nlm.nih.gov/pubmed/35739967
http://dx.doi.org/10.3390/antiox11061069