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Yin and Yang of NADPH Oxidases in Myocardial Ischemia-Reperfusion
Oxidative stress is critically involved in the pathophysiology of myocardial ischemic-reperfusion (I/R) injury. NADPH oxidase (Nox) 2 and 4, major sources of reactive oxygen species (ROS) in cardiomyocytes, are upregulated in response to I/R. Suppression of Nox-derived ROS prevents mitochondrial dys...
Autores principales: | Matsushima, Shouji, Sadoshima, Junichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220061/ https://www.ncbi.nlm.nih.gov/pubmed/35739967 http://dx.doi.org/10.3390/antiox11061069 |
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