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Binding and Efficacy of Anti-Robo4 CAR-T Cells against Solid Tumors

Chimeric antigen receptor expression T (CAR-T) cell therapy has been shown be efficacious against relapsed/refractory B-cell malignant lymphoma and has attracted attention as an innovative cancer treatment. However, cells of solid tumors are less accessible to CAR-T cells; moreover, CAR-T function i...

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Detalles Bibliográficos
Autores principales: Hirobe, Sachiko, Nagai, Seina, Tachibana, Masashi, Okada, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220079/
https://www.ncbi.nlm.nih.gov/pubmed/35740295
http://dx.doi.org/10.3390/biomedicines10061273