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Pharmacokinetics and Pharmacodynamics of Colistin Methanesulfonate in Healthy Chinese Subjects after Multi-Dose Regimen

Colistin methanesulfonate (CMS) is an important treatment option for infections caused by carbapenem-resistant Gram-negative organisms (CROs). This study evaluated the pharmacokinetic/pharmacodynamic (PK/PD) profiles and safety of CMS in Chinese subjects following a recommended dosage. A total of 12...

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Detalles Bibliográficos
Autores principales: Fan, Yaxin, Li, Yi, Chen, Yuancheng, Yu, Jicheng, Liu, Xiaofen, Li, Wanzhen, Guo, Beining, Li, Xin, Wang, Jingjing, Wu, Hailan, Wang, Yu, Hu, Jiali, Guo, Yan, Hu, Fupin, Xu, Xiaoyong, Cao, Guoying, Wu, Jufang, Zhang, Yingyuan, Zhang, Jing, Wu, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220111/
https://www.ncbi.nlm.nih.gov/pubmed/35740204
http://dx.doi.org/10.3390/antibiotics11060798