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Thrombin Activity in Rodent and Human Skin: Modified by Inflammation and Correlates with Innervation

Thrombin is present in peripheral nerves and is involved in the pathogenesis of neuropathy. We evaluated thrombin activity in skin punch biopsies taken from the paws of male mice and rats and from the legs of patients with suspected small-fiber neuropathy (SFN). In mice, inflammation was induced foc...

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Detalles Bibliográficos
Autores principales: Golderman, Valery, Berkowitz, Shani, Guly Gofrit, Shani, Gera, Orna, Aharoni, Shay Anat, Zohar, Daniela Noa, Keren, Daria, Dori, Amir, Chapman, Joab, Shavit-Stein, Efrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220157/
https://www.ncbi.nlm.nih.gov/pubmed/35740482
http://dx.doi.org/10.3390/biomedicines10061461