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Effective Radiosensitization of Bladder Cancer Cells by Pharmacological Inhibition of DNA-PK and ATR

This study aims at analyzing the impact of the pharmacological inhibition of DNA damage response (DDR) targets (DNA-PK and ATR) on radiosensitization of bladder cancer cell lines of different molecular/histological subtypes. Applying DNA-PK (AZD7648) and ATR (Ceralasertib) inhibitors on SCaBER, J82...

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Detalles Bibliográficos
Autores principales: Chughtai, Ahmed Ali, Pannhausen, Julia, Dinger, Pia, Wirtz, Julia, Knüchel, Ruth, Gaisa, Nadine T., Eble, Michael J., Rose, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220184/
https://www.ncbi.nlm.nih.gov/pubmed/35740300
http://dx.doi.org/10.3390/biomedicines10061277