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Ldlr-Deficient Mice with an Atherosclerosis-Resistant Background Develop Severe Hyperglycemia and Type 2 Diabetes on a Western-Type Diet

Apoe(-/-) and Ldlr(-/-) mice are two animal models extensively used for atherosclerosis research. We previously reported that Apoe(-/-) mice on certain genetic backgrounds, including C3H/HeJ (C3H), develop type 2 diabetes when fed a Western diet. We sought to characterize diabetes-related traits in...

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Detalles Bibliográficos
Autores principales: Shi, Weibin, Li, Jing, Bao, Kelly, Chen, Mei-Hua, Liu, Zhenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220196/
https://www.ncbi.nlm.nih.gov/pubmed/35740449
http://dx.doi.org/10.3390/biomedicines10061429