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Ldlr-Deficient Mice with an Atherosclerosis-Resistant Background Develop Severe Hyperglycemia and Type 2 Diabetes on a Western-Type Diet
Apoe(-/-) and Ldlr(-/-) mice are two animal models extensively used for atherosclerosis research. We previously reported that Apoe(-/-) mice on certain genetic backgrounds, including C3H/HeJ (C3H), develop type 2 diabetes when fed a Western diet. We sought to characterize diabetes-related traits in...
Autores principales: | Shi, Weibin, Li, Jing, Bao, Kelly, Chen, Mei-Hua, Liu, Zhenqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220196/ https://www.ncbi.nlm.nih.gov/pubmed/35740449 http://dx.doi.org/10.3390/biomedicines10061429 |
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