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Rapamycin Improves Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Renoprotective Effect against Cisplatin-Induced Acute Nephrotoxicity in Rats by Inhibiting the mTOR/AKT Signaling Pathway

Objective: Because the poor survival of transplanted cells in a hostile microenvironment limits stem cell therapy, in the current study, we investigated the effect of rapamycin (Rapa)-preactivated autophagy on the survival and homing of transplanted adipose mesenchymal stem cells (ADMSCs) in a rat m...

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Detalles Bibliográficos
Autores principales: Awadalla, Amira, Hussein, Abdelaziz M., El-Far, Yousra M., El-Senduny, Fardous F., Barakat, Nashwa, Hamam, Eman T., Abdeen, Hanaa M., El-Sherbiny, Mohamed, Serria, Mohamed S., Sarhan, Amira A., Sena, Asmaa M., Shokeir, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220220/
https://www.ncbi.nlm.nih.gov/pubmed/35740317
http://dx.doi.org/10.3390/biomedicines10061295