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Rapamycin Improves Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Renoprotective Effect against Cisplatin-Induced Acute Nephrotoxicity in Rats by Inhibiting the mTOR/AKT Signaling Pathway
Objective: Because the poor survival of transplanted cells in a hostile microenvironment limits stem cell therapy, in the current study, we investigated the effect of rapamycin (Rapa)-preactivated autophagy on the survival and homing of transplanted adipose mesenchymal stem cells (ADMSCs) in a rat m...
Autores principales: | Awadalla, Amira, Hussein, Abdelaziz M., El-Far, Yousra M., El-Senduny, Fardous F., Barakat, Nashwa, Hamam, Eman T., Abdeen, Hanaa M., El-Sherbiny, Mohamed, Serria, Mohamed S., Sarhan, Amira A., Sena, Asmaa M., Shokeir, Ahmed A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220220/ https://www.ncbi.nlm.nih.gov/pubmed/35740317 http://dx.doi.org/10.3390/biomedicines10061295 |
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