Predicting Antibiotic Effect of Vancomycin Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation: Dense Sampling versus Sparse Sampling

This study aimed to investigate the effect of a structural pharmacokinetic (PK) model with fewer compartments developed following sparse sampling on the PK parameter estimation and the probability of target attainment (PTA) prediction of vancomycin. Two- and three-compartment PK models of vancomycin...

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Detalles Bibliográficos
Autores principales: Kim, Yong Kyun, Lee, Jae Ha, Jang, Hang-Jea, Zang, Dae Young, Lee, Dong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220236/
https://www.ncbi.nlm.nih.gov/pubmed/35740150
http://dx.doi.org/10.3390/antibiotics11060743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220236/
https://www.ncbi.nlm.nih.gov/pubmed/35740150
http://dx.doi.org/10.3390/antibiotics11060743

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