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Predicting Antibiotic Effect of Vancomycin Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation: Dense Sampling versus Sparse Sampling
This study aimed to investigate the effect of a structural pharmacokinetic (PK) model with fewer compartments developed following sparse sampling on the PK parameter estimation and the probability of target attainment (PTA) prediction of vancomycin. Two- and three-compartment PK models of vancomycin...
Autores principales: | Kim, Yong Kyun, Lee, Jae Ha, Jang, Hang-Jea, Zang, Dae Young, Lee, Dong-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220236/ https://www.ncbi.nlm.nih.gov/pubmed/35740150 http://dx.doi.org/10.3390/antibiotics11060743 |
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