Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration

Recent studies suggest that improper resolution of acute neuroinflammation may lead to long-lasting low-grade chronic neuroinflammation and drive progressive neurodegeneration. However, the molecular mechanism underlying the transition from acute to chronic neuroinflammation remains unclear. The mai...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Shih-Heng, Han, Shuangyu, Hu, Chih-Fen, Zhou, Ran, Gao, Yun, Tu, Dezhen, Gao, Huiming, Feng, Jing, Wang, Yubao, Lu, Ru-Band, Hong, Jau-Shyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220294/
https://www.ncbi.nlm.nih.gov/pubmed/35740099
http://dx.doi.org/10.3390/antiox11061202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220294/
https://www.ncbi.nlm.nih.gov/pubmed/35740099
http://dx.doi.org/10.3390/antiox11061202

Ejemplares similares