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Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration

Recent studies suggest that improper resolution of acute neuroinflammation may lead to long-lasting low-grade chronic neuroinflammation and drive progressive neurodegeneration. However, the molecular mechanism underlying the transition from acute to chronic neuroinflammation remains unclear. The mai...

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Detalles Bibliográficos
Autores principales:	Chen, Shih-Heng, Han, Shuangyu, Hu, Chih-Fen, Zhou, Ran, Gao, Yun, Tu, Dezhen, Gao, Huiming, Feng, Jing, Wang, Yubao, Lu, Ru-Band, Hong, Jau-Shyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220294/ https://www.ncbi.nlm.nih.gov/pubmed/35740099 http://dx.doi.org/10.3390/antiox11061202

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