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A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment

Fungal keratitis (FK) pathology is driven by both fungal growth and inflammation within the corneal stroma. Standard in vitro infection models–involving co-culture of the pathogen and the corneal cells in tissue culture medium–are sufficient to probe host responses to the fungus; however, they lack...

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Detalles Bibliográficos
Autores principales: Brown, Marina E., Montgomery, Micaela L., Kamath, Manali M., Nicholas, Sarah, Liu, Yutao, Karamichos, Dimitrios, Fuller, Kevin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220295/
https://www.ncbi.nlm.nih.gov/pubmed/33865843
http://dx.doi.org/10.1016/j.exer.2021.108581