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A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment
Fungal keratitis (FK) pathology is driven by both fungal growth and inflammation within the corneal stroma. Standard in vitro infection models–involving co-culture of the pathogen and the corneal cells in tissue culture medium–are sufficient to probe host responses to the fungus; however, they lack...
Autores principales: | Brown, Marina E., Montgomery, Micaela L., Kamath, Manali M., Nicholas, Sarah, Liu, Yutao, Karamichos, Dimitrios, Fuller, Kevin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220295/ https://www.ncbi.nlm.nih.gov/pubmed/33865843 http://dx.doi.org/10.1016/j.exer.2021.108581 |
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