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Insulin and Its Key Role for Mitochondrial Function/Dysfunction and Quality Control: A Shared Link between Dysmetabolism and Neurodegeneration

SIMPLE SUMMARY: This review will comprise an overview of insulin and its history, structure, synthesis, secretion, signaling, and peripheral and brain roles. Further, the impact that metabolic diseases and the insulin resistance (IR) condition can exert on brain function will be surveyed. Later, att...

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Detalles Bibliográficos
Autores principales: Galizzi, Giacoma, Di Carlo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220302/
https://www.ncbi.nlm.nih.gov/pubmed/35741464
http://dx.doi.org/10.3390/biology11060943