Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation—A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Hypercoagulation and endothelial dysfunction play central roles in severe forms of COVID-19 infections, but the molecular mechanisms involved are unclear. Increased plasma levels of the inflammatory cytokine and TIE2 receptor antagonist Angiopoietin-2 were reported in severely ill COVID-19 patients....

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Detalles Bibliográficos
Autores principales: Hultström, Michael, Fromell, Karin, Larsson, Anders, Persson, Barbro, Nilsson, Bo, Quaggin, Susan E., Betsholtz, Christer, Frithiof, Robert, Lipcsey, Miklos, Jeansson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220312/
https://www.ncbi.nlm.nih.gov/pubmed/35740360
http://dx.doi.org/10.3390/biomedicines10061333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220312/
https://www.ncbi.nlm.nih.gov/pubmed/35740360
http://dx.doi.org/10.3390/biomedicines10061333

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